- Oct 23, 2025
The Link Between Autoimmune Disease and Slowed Metabolism
- Julie Stady
- Hormones, Stress and Metabolism
- 0 comments
If you’re living with an autoimmune condition and feel like your metabolism has completely stalled, you’re not imagining it. Many women with autoimmune disease struggle with fatigue, stubborn weight gain, and a general sense that their body isn’t “firing” like it used to.
But why does this happen? And what can you do about it?
Let’s take a closer look at how autoimmune disease and metabolism are connected and how you can start supporting your body from the roots up.
What Exactly Is Metabolism?
Your metabolism is the process by which your body converts food into energy. It’s what keeps your heart beating, your brain working, and your cells functioning.
But your metabolism isn’t just about burning calories. It’s deeply influenced by your hormones, inflammation levels, gut health, and energy production at the cellular level (your mitochondria).
When any of these systems are disrupted, your metabolism slows down, often without you realizing why. Suddenly, you're 10 pounds heavier and no energy.
How Autoimmune Disease Impacts Metabolism
Autoimmune disease occurs when the immune system mistakenly attacks your body’s own tissues, triggering chronic inflammation. Over time, this inflammation disrupts nearly every metabolic process in the body.
Here’s how it happens:
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Inflammation interferes with thyroid function
The thyroid is your metabolic control center. Chronic inflammation can suppress thyroid hormone production, reducing your basal metabolic rate (the amount of energy your body burns at rest).
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Inflammation damages mitochondria
Mitochondria are your body’s energy factories. When inflammation is high, they become less efficient at producing energy. This leads to fatigue, muscle weakness, and weight gain.
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Digestive dysfunction limits nutrient absorption
Many people with autoimmune conditions also have gut permeability (“leaky gut”) and poor digestion. This limits your ability to absorb key nutrients like B vitamins, iron, and magnesium. All micronutrients are crucial for metabolic function.
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Hormonal disruption amplifies fatigue
Chronic inflammation raises cortisol and throws off estrogen, progesterone, and insulin balance. These hormonal shifts can cause energy crashes, cravings, and slower fat metabolism.
Why Conventional Approaches Often Miss the Mark
Most conventional treatments focus on suppressing the immune system or managing symptoms - without addressing what’s happening underneath.
You might be told that your thyroid labs are “normal,” even when you’re experiencing fatigue, brain fog, and weight gain.
The truth? Many women with autoimmune conditions fall into a “subclinical” zone - one of the 3 stages of autoimmune disease - where their metabolism is already slowing, but it doesn’t yet meet the threshold for a medical diagnosis.
A functional approach looks deeper. Instead of just managing the disease, it asks why your body is inflamed, sluggish, or out of balance—and helps you restore the foundation.
3 Functional Ways to Reignite Your Metabolism
Here’s where healing from the roots begins:
Nourish your soil with anti-inflammatory foods
Focus on whole, nutrient-dense foods such as wild salmon, leafy greens, olive oil, bone broth, and colorful vegetables. These calm inflammation and provide essential nutrients for energy production.Support gut health daily
Your gut influences your metabolism more than you realize. Repairing the gut lining, rebalancing microbes, and reducing food sensitivities can boost energy and regulate inflammation.Balance rest and movement
Over-exercising can worsen inflammation, while too little activity slows metabolism. Choose restorative movement like walking, yoga, resistance training and prioritize deep, consistent sleep to support recovery.
The Bottom Line
Autoimmune disease doesn’t just attack your immune system - it can quietly drain your metabolic power, too.
But by calming inflammation, nourishing your gut, and supporting your hormones, you can help your metabolism recover and restore your energy naturally.
Healing your metabolism isn’t about dieting or deprivation - it’s about creating the right environment for your body to thrive.
Nourish your soil. Calm your roots. Tame your branches. Thrive again.
Want to dive deeper and learn how to thrive with autoimmune disease? Check our my signature autoimmune reset program!
Healthy regards,
Julie
julie@revealhealthfnc.com